CD3E (clone 4E2), anti-human

CD3E (clone 4E2), anti-human

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In stock
SKU
BT-MCA4396
Catalog Number: BT-MCA4396
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): WB, FCM
Datasheet
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Background:
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Research Area: Immunology

Synonyms: T3E, TCRE, FLJ18683, CD3E

Immunogen: Purified recombinant fragment of CD3E expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage
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