CD3E polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Synonyms: IMD18, T3E, TCRE

Cellular Location: Cell membrane Single-pass type I membrane protein

Immunogen:
Recombinant protein of human CD3E

Gene Symbol: CD3E

Gene ID: 916

Swiss prot: P07766

Calculated MW: 23kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IP 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.