CD3G polyclonal, anti-human, mouse

Background:
The T cell antigen receptor (TCR) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. Much of this signaling process can be attributed to a multisubunit complex of proteins that associates directly with the TCR. This complex has been designated CD3 (cluster of differentiation 3). It is composed of five invariant polypeptide chains that associate to form three dimers: a heterodimer of gamma and epsilon chains (γε), a heterodimer of delta and epsilon chains (δε) and a homodimer of two zeta chains (ζζ) or a heterodimer of zeta and eta chains (ζη). The ζ and η chains are encoded by the same gene but differ in their carboxyl-terminal ends due to an alternative splicing event. The γ, ε and δ chains each contain a single copy of a conserved immunoreceptor tyrosine-based activation motif (ITAM).

Alternative Name:
CD3G, T3G, CD3 gamma, CD3-GAMMA, CD3g, CD3g antigen gamma polypeptide (TiT3 complex), CD3g antigen gamma polypeptide, CD3g molecule gamma (CD3 TCR complex), CD3g molecule gamma, CD3G, FLJ17620, FLJ17664, FLJ79544, FLJ94613, MGC138597, T cell antigen receptor complex gamma subunit of T3, T-cell receptor T3 gamma chain, T-cell surface glycoprotein CD3 gamma chain, T3G,

Application Dilution:
WB:1:500-1:1,000
IHC:1:50-1:200
FC:1:50-1:100
IP:1:10-1:50

Specificity: CD3G polyclonal antibody detects endogenous levels of CD3G protein.

Immunogen:
Recombinant protein

MW: 20 kDa

Swiss-Prot: P09693(Human) P11942(Mouse)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.