CD4 Antibody (N-term) Blocking Peptide

Background:
CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes (helper/inducer T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.

Other Names:
T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4, CD4

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1496a was selected from the N-term region of human CD4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: CD4

Gene ID: 920
Primary Accession: P01730
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.