CD4 (clone 3A12A5), anti-
€0.00
In stock
SKU
BT-MCA4293
Catalog Number: BT-MCA4293
Size(s): 50μL, 100μL
Isotype: Mouse IgG2b
Reactivity:
Application(s): FCM
Datasheet
Request Information
Size(s): 50μL, 100μL
Isotype: Mouse IgG2b
Reactivity:
Application(s): FCM
Datasheet
Request Information
Background:
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Research Area: Immunology
Synonyms: IMD79, OKT4D, CD4mut
Immunogen: Purified recombinant fragment of human CD4 (AA: 26-170) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Research Area: Immunology
Synonyms: IMD79, OKT4D, CD4mut
Immunogen: Purified recombinant fragment of human CD4 (AA: 26-170) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
| Is Featured? | No |
|---|
Write Your Own Review