CD4 (clone 7H9), anti-human, mouse, rat

Backgroud: Cluster of Differentiation 4 (CD4) is a glycoprotein composed of an amino-terminal extracellular domain (four domains: D1-D4 with Ig-like structures), a transmembrane part and a short cytoplasmic tail. CD4 is expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages and dendritic cells, and plays an important role in the development and activation of T cells. On T cells, CD4 is the co-receptor for the T cell receptor (TCR), and these two distinct structures recognize the Antigen–Major Histocompatibility Complex (MHC).

Synonyms: CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD antigen CD4

Gene Name: CD4

Gene ID: 920

SwissProt ID: P01730

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.