CD4 (clone E9) (06-1034-2), anti-human

Background:
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Decription:
Mouse monoclonal Antibody to Human CD4 clone E9

Synonyms: CD4

Clone: E9

Isotype: Mouse IgG2b

Immunogen: Purified Human CD4+ peripheral blood T cells

Reactivity: human

Specificity: Clone E9 detects Human CD4

Form: Affinity Purified, in PBS containing 0.5% BSA and 0.1% Sodium Azide

Applications: Flow cytometry, immunohistochemistry

Working Dilution: Titer for blocking of HIV infection has to be determined by user

Storage: 2-8C for immediate use; or at -20C (aliquot) Avoid freeze-thaw cycles