CD4 polyclonal, anti-human, mouse, rat, monkey, sheep, pig, dog

Protein Family: Cellular Antigens, Cell Adhesion Molecules, CAM Ligands

Pathway and Disease: Immune System, Signaling Molecules and Interaction

Description:
CD4 antigen is found on a T-cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. CD4 is also present on 80% of thymocytes and at a lower level on monocytes. CD4 is involved in recognition of antigen presented along with MHC class II by APCs. CD4 is the primary cellular receptor for the human immunodeficiency virus (HIV).

Alternate Names: T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:50-1:500

Accession No.: P01730

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region (cytoplasmic) of human CD4.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
[1]Borrione P et al. 2013. Dept. Health Science. University of Rome. Blood Transfus. Doi: 10.2450/2013.0275-12
[2] Oh H et al. Journal of Pharmacology and Experimental Therapeutics. 339(1):72-81. PMID# 2730010.
[3] Samokhin A.O. et al. 2010. Am. J. Pathol. 176: 1148-1156. PMID# 21554502.