CD4 polyclonal HRP, anti-human, mouse, rat, monkey, sheep, pig, dog

Protein Family: Cellular Antigens, Cell Adhesion Molecules, CAM Ligands

Pathway and Disease: Immune System, Signaling Molecules and Interaction

Description:
CD4 antigen is found on a T-cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. CD4 is also present on 80% of thymocytes and at a lower level on monocytes. CD4 is involved in recognition of antigen presented along with MHC class II by APCs. CD4 is the primary cellular receptor for the human immunodeficiency virus (HIV).

Alternate Names: T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4

Application Notes: Product Cat. No. 252255 is the HRP conjugate of Cat. No. 250592. E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:50-1:500

Accession No.: P01730

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD4.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA and 0.02% gentamicin. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Product is guaranteed 6 months from the date of shipment.

Product Citations:
Zhang J et al. 2012. Biomedical and Life Sciences. Molecular Biology Reports. 40(2):949-956. PMID# 23065281.