CD4 (T-Helper/Inducer Cell Marker) (clone C4/206 ), anti-human

Background:
Recognizes a protein of 55kDa, identified as CD4. CD4 is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.Ā

Other Names:
T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4, CD4

Gene Name: CD4
Gene ID: 920
Primary Accession: P01730
Other Accession: 920, 631659