CD4 (T-Helper/Inducer Cell Marker) (clone EDU-2 ), anti-human, chimpanzee

Background:
Recognizes a protein of 55kDa, identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.ĀThis MAb was characterized as human CD4 antibody at II and IV International Workshop on Human Leukocyte Differentiation Antigens.

Other Names:
T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4, CD4

Gene Name: CD4
Gene ID: 920
Primary Accession: P01730
Other Accession: 920, 631659