CD41/Integrin α/2b Mouse mAb

Background:
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation.

Cellular localization: Membrane

Specificity: Human

Alternative Names:
BDPLT2,CD41 antigen, CD41a, gp2b, ITGA2B, platelet fibrinogen receptor alpha

Immunogen: Synthetic Peptide

Isotype: Mouse Monoclonal IgG1

Concentration: 1mg/ml

Recommended dilutions: IHC 1:100-200

GeneID: 3674

Swiss-Prot No.: P08514

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid repeated freeze-thaw cycles.

NOTE: For Research Use Only