CD43 [clone DF-T1], anti-human

Description: CD43 (leukosialin, sialophorin, or leukocyte sialoglycoprotein) is a cell surface glycoprotein which is expressed on all thymocytes and T-cells. CD43 is involved in activation of T cells, B cells, NK cells, and monocytes.From 70 to 90% of T-cell Lymphomas and from 22 to 37% of B cell Lymphomas are labeled with this antibody. No reactivity has been observed with reactive B cells. So, a B lineage population that co-expresses a T-cell marker is highly likely to be a malignant lymphoma rather than a reactive B cell population. When used in combination with CD45 and L26, effective immunophenotyping of the majority of paraffin-embedded lymphomas can be obtained. Co-staining of a lymphoid infiltrate with CD20 and CD3 argues against a reactive process and favors lymphoma.Localization: membraneDilution: 50-200Positive Control: tonsil, CLL/SLL, lymph nodeHIER: citrate pH6.0Status: RUO