CD44 (clone N58-2), anti-human
€0.00
In stock
SKU
BMA1010
Catalog Number: BMA1010
Size: 100 μg
Isotype: Mouse IgM
Reactivity: human
Application(s): WB, IHC-P, Flow-Cyt
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Size: 100 μg
Isotype: Mouse IgM
Reactivity: human
Application(s): WB, IHC-P, Flow-Cyt
Request Information
Background:
The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. In humans, the CD44 antigen is encoded by the CD44 gene.1The CD44 molecule is known to display extensive size heterogeneity, which has been attributed both to alternative splicing and to differential glycosylation within the extracellular domain. The human CD44 gene contains at least 19 exons spanning some 50 kilobases of DNA.2CD44 is necessary for limb development and functions in a novel growth factor presentation mechanism likely relevant in other physiological and pathological situations where a cell surface protein presents a signaling molecule to a neighboring cell.3CD44 also plays a pivotal role in arteriogenesis.4
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the extracellular region of human CD44.
Recommended Application:
Western Blot, WB (1:200-1:500); Immunohistochemistry, IHC-P(1:100); Flow Cytometry, Flow-Cyt (1:50-1:100)
Product Form: Liquid
Purification: Immunogen affinity purified.
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. In humans, the CD44 antigen is encoded by the CD44 gene.1The CD44 molecule is known to display extensive size heterogeneity, which has been attributed both to alternative splicing and to differential glycosylation within the extracellular domain. The human CD44 gene contains at least 19 exons spanning some 50 kilobases of DNA.2CD44 is necessary for limb development and functions in a novel growth factor presentation mechanism likely relevant in other physiological and pathological situations where a cell surface protein presents a signaling molecule to a neighboring cell.3CD44 also plays a pivotal role in arteriogenesis.4
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the extracellular region of human CD44.
Recommended Application:
Western Blot, WB (1:200-1:500); Immunohistochemistry, IHC-P(1:100); Flow Cytometry, Flow-Cyt (1:50-1:100)
Product Form: Liquid
Purification: Immunogen affinity purified.
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
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