CD44 Polyclonal Antibody

Background:
CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration,tumor growth and progression. CD44 is also involved in lymphocyte activation,recirculation and homing,and in hematopoiesis. This protein exists in multiple isoforms (with molecular weight ranging from 16 kDa to over 200 kDa) generated by alternative RNA splicing and undergoes extensive post-translational modifications.

Research Area: Cancer, Immunology, Stem Cells, Kits/ Lysates/ Other

Synonyms:
LHR, BA-1, CD44 antigen, CD44 molecule, Cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, CSPG8, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor , HCELL, HAS, HUTCH1, PGP-1, Phagocytic glycoprotein 1

Immunogen: Recombinant Rat CD44 antigen protein

Swissprot: P26051
Gene ID: 25406

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:100-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.