CD45 (clone 2H12), anti-human
€254.00
In stock
SKU
ARP-05-50130-2
Catalog Number: 05-50130-2
Size: 200 µl
Isotype: IgG2b, k
Size: 200 µl
Isotype: IgG2b, k
Background:
Mouse Monoclonal
Decription:
CD45 belongs to a family of heavily glycosylated, high molecular weight transmembrane glycoproteins expressed on all cells of haematopoietic origin. Structurally heterogeneous, CD45 consists of a family of eight isoforms ranging from 180,000 to 220,000 MW generated by alternative splicing of three exons differentially expressed on subpopulation of lymphocytes. CD45 protein tyrosine phosphatase activity plays a central role in T-cell activation. CD45 plays an important role in signal transduction inhibition or upregulation of various immunological functions.
Synonyms: protein tyrosine phosphatase, receptor type, C (PTPRC), CD45
Clone: 2H12. Anti-human CD45 mAb, clone 2H12, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CD45 protein.
Isotype: IgG2b, k
Immunogen: Recombinant human CD45 (1029-1249aa) purified from E. coli
Reactivity: human
Form: Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
Applications: ELISA, FACS
Working Dilution: Optimal dilution should be performed by user.
NCBI Nr.: NM_002838
Concentration: 0.1 mg/ml
Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Mouse Monoclonal
Decription:
CD45 belongs to a family of heavily glycosylated, high molecular weight transmembrane glycoproteins expressed on all cells of haematopoietic origin. Structurally heterogeneous, CD45 consists of a family of eight isoforms ranging from 180,000 to 220,000 MW generated by alternative splicing of three exons differentially expressed on subpopulation of lymphocytes. CD45 protein tyrosine phosphatase activity plays a central role in T-cell activation. CD45 plays an important role in signal transduction inhibition or upregulation of various immunological functions.
Synonyms: protein tyrosine phosphatase, receptor type, C (PTPRC), CD45
Clone: 2H12. Anti-human CD45 mAb, clone 2H12, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CD45 protein.
Isotype: IgG2b, k
Immunogen: Recombinant human CD45 (1029-1249aa) purified from E. coli
Reactivity: human
Form: Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
Applications: ELISA, FACS
Working Dilution: Optimal dilution should be performed by user.
NCBI Nr.: NM_002838
Concentration: 0.1 mg/ml
Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
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