CD45 polyclonal, anti-
€0.00
In stock
SKU
AC-AP22447a
Catalog Number: AC-AP22447a
Size: 50 µl, 200 µl
Isotype: Rabbit Ig
Clone Name: R03408
Applications: WB
Datasheet
Request Information
Size: 50 µl, 200 µl
Isotype: Rabbit Ig
Clone Name: R03408
Applications: WB
Datasheet
Request Information
Background:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor (PubMed:35767951). Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
Other Names:
Receptor-type tyrosine-protein phosphatase C, 3.1.3.48, Leukocyte common antigen, L-CA, T200, CD45, PTPRC (HGNC:9666), CD45
Target/Specificity:
This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.
Antigen Type: Recombinant Protein
Gene Name: PTPRC (HGNC:9666)
Gene ID: 5788
Primary Accession: P08575
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor (PubMed:35767951). Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
Other Names:
Receptor-type tyrosine-protein phosphatase C, 3.1.3.48, Leukocyte common antigen, L-CA, T200, CD45, PTPRC (HGNC:9666), CD45
Target/Specificity:
This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.
Antigen Type: Recombinant Protein
Gene Name: PTPRC (HGNC:9666)
Gene ID: 5788
Primary Accession: P08575
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
|---|
Write Your Own Review