CD46 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP4785b
Catalog Number: AC-AP4785b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21743
Applications: WB, IF, FC, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21743
Applications: WB, IF, FC, IHC-P
Datasheet
Request Information
Background:
CD46 is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system.
Other Names:
Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen, CD46, CD46, MCP, MIC10
Target/Specificity:
This CD46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-343 amino acids from the C-terminal region of human CD46.
Antigen Region:
317-343
Antigen Type: Synthetic Peptide
Gene Name: CD46
Gene ID: 4179
Primary Accession: P15529
NCBI Accession: NP_002380.3;NP_722548.1;NP_758860.1;NP_758861.1;NP_758862.1;NP_758863.1;NP_758869.1;NP_758871.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
CD46 is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system.
Other Names:
Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen, CD46, CD46, MCP, MIC10
Target/Specificity:
This CD46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-343 amino acids from the C-terminal region of human CD46.
Antigen Region:
317-343
Antigen Type: Synthetic Peptide
Gene Name: CD46
Gene ID: 4179
Primary Accession: P15529
NCBI Accession: NP_002380.3;NP_722548.1;NP_758860.1;NP_758861.1;NP_758862.1;NP_758863.1;NP_758869.1;NP_758871.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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