CD47 polyclonal, anti-human, rat

Quantity: 100 µg

Background:
CD47, also known as IAP or MER6, is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 gene belongs to the immunoglobulin superfamily. This gene is mapped to 3q13.12. CD47 gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes.

Description:
Rabbit IgG polyclonal antibody for Leukocyte surface antigen CD47 (CD47) detection. Tested with WB, IHC-P in Human, Rat.

Synonyms:
Antigenic surface determinant protein OA3 antibody, CD 47 antibody, CD47 antibody, Cd47 antibody, CD47 antigen(Rh-related antigen, integrin-associated signal transducer) antibody, CD47 antigen antibody, CD47 glycoprotein antibody, CD47 molecule antibody, CD47_HUMAN antibody, IAP antibody, Integrin Associated Protein antibody, Integrin associated signal transducer antibody, Integrin-associated protein antibody, Leukocyte surface antigen CD47 antibody, MER 6 antibody, MER6 antibody, OA 3 antibody, OA3 antibody, OTTHUMP00000041152 antibody, OTTHUMP00000041153 antibody, Protein MER6 antibody, Rh related antigen antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human CD47(308-323aa EPLNAFKESKGMMNDE), identical to the related rat sequence.A synthetic peptide corresponding to a sequence at the C-terminus of human CD47(308-323aa EPLNAFKESKGMMNDE), identical to the related rat sequence.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.