CD49c (Integrin alpha 3) polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
ITGA3(INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.

Description:
Rabbit IgG polyclonal antibody for Integrin alpha-3 (ITGA3) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
AA407068 antibody, Antigen identified by monoclonal antibody J143 antibody, CD49 antigen like family member C antibody, CD49 antigen-like family member C antibody, CD49c antibody, CD49c antigen antibody, FLJ34631 antibody, FLJ34704 antibody, FRP 2 antibody, FRP-2 antibody, FRP2 antibody, galactoprotein B3 antibody, GAP B3 antibody, GAPB3 antibody, Integrin alpha 3 antibody, Integrin alpha-3 light chain antibody, Integrin, alpha 3(antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody, ITA3_HUMAN antibody, ITGA 3 antibody, ITGA3 antibody, MSK18 antibody, URO1 antibody, VCA 2 antibody, VCA2 antibody, Very late activation protein 3 receptor alpha 3 subunit antibody, Very Late Activation Protein 3 Receptor Alpha 3 Subunit antibody, VL3A antibody, VLA 3 alpha chain antibody, VLA 3 subunit alpha antibody, VLA-3 subunit alpha antibody, VLA3 antibody, VLA3a antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human Integrin alpha 3(51-67aa LFGYSVALHRQTERQQR), identical to the related rat and mouse sequences.A synthetic peptide corresponding to a sequence at the N-terminus of human Integrin alpha 3(51-67aa LFGYSVALHRQTERQQR), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.