CD49f (Integrin alpha 6) polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Integrin alpha-6, also called VLA-6 or ITGA6B is a protein that in humans is encoded by the ITGA6 gene. This gene is mapped to 2q31.1. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome.

Description:
Rabbit IgG polyclonal antibody for Integrin alpha-6 (ITGA6) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Alpha 6 antibody, CD49 antigen-like family member F antibody, CD49f antibody, Integrin alpha chain antibody, Integrin alpha-6 light chain antibody, Integrin alpha6B antibody, Integrin, alpha 6 antibody, ITA6_HUMAN antibody, ITGA 6 antibodyITGA6 antibody, ITGA6B antibody, VLA 6 alpha subunit antibody, VLA 6 antibody, VLA-6 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human Integrin alpha 6(24-37aa FNLDTREDNVIRKY), different from the related mouse and rat sequences by one amino acid.A synthetic peptide corresponding to a sequence at the N-terminus of human Integrin alpha 6(24-37aa FNLDTREDNVIRKY), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.