CD5 (Mantle Cell Lymphoma Marker) (clone CRIS-1), anti-human, rhesus monkey

CD5 (Mantle Cell Lymphoma Marker) (clone CRIS-1), anti-human, rhesus monkey

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In stock
SKU
ARP-24-921-MSM4
Catalog Number: 24-921-MSM4
Size: 100 µl, 0.5 ml, 1 ml
Isotype: Mouse IgG2a, kappa
Decription:
Recognizes a 67kDa transmembrane protein, which is identified as CD5 (HLDA I; WS Code T 29HLDA III; WS Code T 530). The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms.

Synonyms: CD5 antigen (p56 62), LEU1, Ly12, LyA, Lymphocyte antigen T1/Leu-1, Lymphocyte glycoprotein T1/Leu1, T-cell surface glycoprotein CD5

Clone: CRIS-1

Isotype: Mouse IgG2a, kappa

Immunogen: Stimulated human leukocytes

Reactivity: human and rhesus monkey. Others not-tested.

Form: Purified, in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Applications: Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Immunofluorescence (0.5-1ug/ml)
Functional Studies (Order Ab without BSA & Azide)
Immunoprecipitation (0.5-1 �g/500ug protein Lysate)
Optimal dilution for a specific application should be determined.

Reactivity: 293T, Ramos, or MOLT-4 Cells. Tonsil.

Concentration: 0.2mg/ml

Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
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