CD54 (ICAM-1) polyclonal, anti-mouse, rat

Quantity: 100 µg

Background:
Intercellular adhesion molecule-1 (ICAM-1) is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for lymphocyte function-associated (LFA) antigens, a beta 2 leukocyte integrin. The normal function of human ICAM-1 is to provide adhesion between endothelial cells and leukocytes after injury or stress. ICAM-1 binds to leukocyte function-associated antigen (LFA-1) or macrophage-1 antigen (Mac-1). It is found on leukocytes, fibroblasts, epithelial cells and endothelial cells and its expression is regulated by inflammatory cytokines. ICAM-1 has a tissue distribution similar to that of the major histocompatibility complex class II antigens and is likely to play a role in inflammatory responses.

Description:
Rabbit IgG polyclonal antibody for Intercellular adhesion molecule 1 (ICAM1) detection. Tested with WB, IHC-P in Mouse, Rat.

Synonyms:
Antigen identified by monoclonal antibody BB2 antibody, BB 2 antibody, BB2 antibody, CD 54 antibody, CD_antigen, CD54 antibody, CD54 antigen antibody, Cell surface glycoprotein P3.58 antibody, Human rhinovirus receptor antibody, ICAM 1 antibody, ICAM-1 antibody, ICAM1 antibody, ICAM1_HUMAN antibody, intercellular adhesion molecule 1(CD54), human rhinovirus receptor antibody, Intercellular adhesion molecule 1 antibody, Major group rhinovirus receptor antibody, MALA 2 antibody, MALA2 antibody, MyD 10 antibody, MyD10 antibody, P3.58 antibody, Surface antigen of activated B cells antibody, Surface antigen of activated B cells, BB2 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived mouse ICAM1 recombinant protein (Position: G198-P537). Mouse ICAM1 shares 74% amino acid (aa) sequence identity with rat ICAM1.E.coli-derived mouse ICAM1 recombinant protein (Position: G198-P537). Mouse ICAM1 shares 74% amino acid (aa) sequence identity with rat ICAM1.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.