CD54 polyclonal, anti-mouse, rat

Protein Family: CAM Ligands, Cell Adhesion Molecules, Cellular Antigens, Glycan Binding Proteins

Pathway and Disease: Immune System, Signaling Molecules and Interaction

Description:
ICAM-1 (Intracellular adhesion molecule 1) is the ligand for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM-1 promotes the assembly of endothelial apical cups through SGEF and RHOG activation. ICAM-1 is a cellular receptor for rhinoviruses.

Alternate Names: Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, CD54 antigen, ICAM1

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P05362

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of mouse ICAM-1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
[1] Mikrou A et al. 2016. Mol Immunol. 72: 1-8. PMID 26922039.
[2] Schmutzhard J et al. 2011. Tropical Medicine & International Health. 16(8):914-922. PMID 21554502.