CD54 Polyclonal Antibody

Background:
ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues . ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin . It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum .

Research Area: Cancer, Cardiovascular, Immunology, Stem Cells

Synonyms:
Antigen identified by monoclonal BB2, BB 2, BB2, CD 54, CD_antigen=CD54, CD54, Cell surface glycoprotein P3.58, Human rhinovirus receptor, ICAM 1, ICAM-1, ICAM1, ICAM1, intercellular adhesion molecule 1 (CD54), human rhinovirus receptor, Intercellular adhesion molecule 1, Major group rhinovirus receptor, MALA 2, MALA2, MyD 10, MyD10, P3.58, Surface antigen of activated B cells, BB2

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse ICAM-1

Swissprot: P05362,Q00238,P13597

Calculated MW: 58 kDa
Observed MW: 58 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 0.84 mg/mL
Dilution: WB 1:1000-1:3000, IHC 1:500-1:1000, IF 1:200-1:800

Storage:
Store at -20°C. Avoid freeze / thaw cycles.