CD58 polyclonal, anti-human, mouse, rat antibody

Background:
CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of its cognate ligand, CD2, on the T cell surface.

Other Names:
LFA3, Lymphocyte function-associated antigen 3, Ag3, Surface glycoprotein LFA-3, CD58

Primary Accession: P19256

Gene Name: CD58

Gene ID: 965

Concentration (mg/ml): 1 mg/ml