CD58 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5657
Background:
CD2 (also designated E-rosette receptor) interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on T lymphocytes, NK cells and thymocytes, as well as on mouse B cells and rat splenic macrophages. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium.
Alternative Name:
Lymphocyte function-associated antigen 3, Ag3, Surface glycoprotein LFA-3, LFA3
Application Dilution: WB: 1:500~1:1000
Specificity: CD58 polyclonal antibody detects endogenous levels of CD58 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 78-123 of Human CD58.
MW: ~ 65-70 kDa
Swis Prot.: P19256
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
CD2 (also designated E-rosette receptor) interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on T lymphocytes, NK cells and thymocytes, as well as on mouse B cells and rat splenic macrophages. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium.
Alternative Name:
Lymphocyte function-associated antigen 3, Ag3, Surface glycoprotein LFA-3, LFA3
Application Dilution: WB: 1:500~1:1000
Specificity: CD58 polyclonal antibody detects endogenous levels of CD58 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 78-123 of Human CD58.
MW: ~ 65-70 kDa
Swis Prot.: P19256
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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