CD59 polyclonal, anti-human

Quantity: 100 µg

Background:
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. And this protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. It also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Description:
Rabbit IgG polyclonal antibody for CD59 glycoprotein (CD59) detection. Tested with IHC-P in Human.

Synonyms:
16.3A5 antibody, 1F5 antibody, 1F5 antigen antibody, 20 kDa homologous restriction factor antibody, CD 59 antibody, CD_antigen=CD59 antibody, CD59 antibody, CD59 antigen antibody, CD59 antigen complement regulatory protein antibody, CD59 antigen p18 20 antibody, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) antibody, CD59 glycoprotein antibody, CD59 molecule antibody, CD59 molecule complement regulatory protein antibody, CD59_HUMAN antibody, Cd59a antibody, Complement regulatory protein antibody, EJ16 antibody, EJ30 antibody, EL32 antibody, FLJ38134 antibody, FLJ92039 antibody, G344 antibody, HRF 20 antibody, HRF-20 antibody, HRF20 antibody, Human leukocyte antigen MIC11 antibody, Ly 6 like protein antibody, Lymphocytic antigen CD59/MEM43 antibody, MAC inhibitory protein antibody, MAC IP antibody, MAC-inhibitory protein antibody, MAC-IP antibody, MACIF antibody, MACIP antibody, MEM43 antibody, MEM43 antigen antibody, Membrane attack complex (MAC) inhibition factor antibody, Membrane attack complex inhibition factor antibody, Membrane inhibitor of reactive lysis antibody, MGC2354 antibody, MIC11 antibody, MIN1 antibody, MIN2 antibody, MIN3 antibody, MIRL antibody, MSK21 antibody, p18 20 antibody, Protectin antibody, Surface antigen recognized by monoclonal antibody, 16.3A5 antibody, T cell activating protein antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CD59 recombinant protein (Position: L26-N102). Human CD59 shares 47.1% amino acid (aa) sequence identity with rat CD59.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.