CD6 (clone SPV-L14 ), anti-human, mouse
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In stock
SKU
AC-AH12620
Catalog Number: AC-AH12620
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPV-L14
Applications: IF, FC
Datasheet
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Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPV-L14
Applications: IF, FC
Datasheet
Request Information
Background:
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular �scavenger receptor cysteine-rich� (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Other Names:
T-cell differentiation antigen CD6, T12, TP120, CD6, CD6
Gene Name: CD6 (HGNC:1691)
Gene ID: 923
Primary Accession: P30203
Other Accession: 923, 744366
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular �scavenger receptor cysteine-rich� (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Other Names:
T-cell differentiation antigen CD6, T12, TP120, CD6, CD6
Gene Name: CD6 (HGNC:1691)
Gene ID: 923
Primary Accession: P30203
Other Accession: 923, 744366
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