CD61 (Integrin beta-3, Platelet Marker) (clone 25E11.), anti-human

CD61 (Integrin beta-3, Platelet Marker) (clone 25E11.), anti-human

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In stock
SKU
ARP-24-3690-MSM1
Catalog Number: 24-3690-MSM1
Size: 100 µl, 0.5 ml, 1 ml
Isotype: Mouse IgM, kappa
Decription:
Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). The protein detectable is a complex of CD41 and CD61.The apparent molecular weight of the GPIIIa by SDS-PAGE is 105kDa reduced and 90kDa unreduced. Ligands are fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding.Ā

Synonyms: BDPLT2, GP3A, GPIIIa, GT, HPA 1, HPA 4, Integrin beta-3, ITGB3, NAIT, Platelet fibrinogen receptor beta subunit, Platelet glycoprotein IIIa, PTP

Clone: 25E11.

Isotype: Mouse IgM, kappa

Immunogen: Normal blood mononuclear cells activated by mixed lymphocyte reaction

Reactivity: human. Others not-tested.

Form: Purified, in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Applications: Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Immunofluorescence (0.5-1ug/ml)
Inhibits platelet aggregation (Order Ab without Azide)
Optimal dilution for a specific application should be determined.

Reactivity: U937, KG1a, HEL cells, and human platelets in lymph nodes or tonsils.

Concentration: 0.2mg/ml

Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
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