CD62L polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
CD62L, also known as L-selectin, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.

Description:
Rabbit IgG polyclonal antibody for L-selectin (SELL) detection. Tested with WB, IHC-P, ELISA in Human, Mouse, Rat.

Synonyms:
A.11 antibody, AI528707 antibody, CD62 antigen ligand antibody, CD62 antigen-like family member L antibody, CD62L antibody, gp90 MEL antibody, gp90-MEL antibody, hLHRc antibody, IgA nephropathy, susceptibility to, included antibody, L Selectin antibody, L-selectin antibody, LAM-1 antibody, LAM1 antibody, LECAM1 antibody, LEU8 antibody, Leukocyte adhesion molecule 1 antibody, Leukocyte surface antigen Leu-8 antibody, Leukocyte surface antigen Leu8 antibody, Leukocyte-endothelial cell adhesion molecule 1 antibody, LNHR antibody, LSEL antibody, Ly-22 antibody, Ly-m22 antibody, Lyam-1 antibody, LYAM1 antibody, LYAM1_HUMAN antibody, Lymph node homing receptor antibody, Lymphocyte adhesion molecule 1 antibody, Lymphocyte antigen 22 antibody, Lymphocyte surface MEL-14 antigen antibody, MEL-14 antibody, Pln homing receptor antibody, PLNHR antibody, Selectin L antibody, Selectin, lymphocyte antibody, SELL antibody, TQ1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E. coli-derived human CD62L recombinant protein (Position: W39-Y372). Human CD62L shares 77.5 % and 78.7 % amino acid (aa) sequence identity with mouse and rat CD62L, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.