CD62P polyclonal, anti-human

Quantity: 100 µg

Background:
CD62P is also known as SELP or P-selectin. This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. 

Description:
Rabbit IgG polyclonal antibody for P-selectin (SELP) detection. Tested with WB, IHC-P, ELISA in Human.

Synonyms:
Antigen CD62 antibody, CD62 antibody, CD62 antigen-like family member P antibody, CD62P antibody, GMP 140 antibody, GMP-140 antibody, GMP140 antibody, GMRP antibody, Granule membrane protein 140 antibody, Granulocyte membrane protein antibody, GRMP antibody, LECAM 3 antibody, LECAM3 antibody, Leukocyte endothelial cell adhesion molecule 3 antibody, Leukocyte-endothelial cell adhesion molecule 3 antibody, LYAM3_HUMAN antibody, P Selectin antibody, P-selectin antibody, PADGEM antibody, Platelet activation dependent granule-external membrane protein antibody, Platelet alpha granule membrane protein antibody, PSEL antibody, Selectin P (granule membrane protein 140kDa, antigen CD62) antibody, SELP antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CD62P recombinant protein (Position: W42-G271). Human CD62P shares 75% and 76% amino acid (aa) sequence identity with mouse and rat CD62P, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.