CD63 (clone ), anti-human antibody

Background:
Anti-CD63 recognizes an extracellular fragment of CD63, a 56-kilodalton (kDa), type III lysosomal glycoprotein, belonging to the tetraspanin family. CD63 is expressed by granulocytes, platelets, T-cells, monocytes/macrophages, endothelial cells. CD63 protein is also expressed in exosome membrane. Cell sur-face exposition of CD63 is usually activation dependent. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell co-stimulator molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas.

Other Names:
CD63 antigen, Granulophysin, Lysosomal-associated membrane protein 3, LAMP-3, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen, Tetraspanin-30, Tspan-30, CD63, CD63, MLA1, TSPAN30

Primary Accession: P08962

Gene Name: CD63

Gene ID: 967

Concentration (mg/ml): 1 mg/ml