CD63 polyclonal, anti-human

Quantity: 100 µg

Background:
CD63 antigen is a protein that in humans is encoded by the CD63 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. It is mapped to 12q13.2. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression.

Description:
Rabbit IgG polyclonal antibody for CD63 antigen (CD63) detection. Tested with WB, IHC-P in Human.

Synonyms:
Lysosomal associated membrane protein 3 antibody, CD 63 antibody, CD63 antibody, CD63 antigen (melanoma 1 antigen) antibody, CD63 antigen antibody, CD63 antigen melanoma 1 antigen antibody, CD63 molecule antibody, CD63_HUMAN antibody, gp55 antibody, granulophysin antibody, LAMP 3 antibody, LAMP-3 antibody, LAMP3 antibody, LIMP antibody, Lysosomal-associated membrane protein 3 antibody, lysosome associated membrane glycoprotein 3 antibody, Mast cell antigen AD1 antibody, ME491 antibody, melanoma 1 antigen antibody, Melanoma associated antigen ME491 antibody, Melanoma associated antigen MLA1 antibody, Melanoma-associated antigen ME491 antibody, MGC72893 antibody, MLA 1 antibody, MLA1 antibody, NGA antibody, ocular melanoma associated antigen antibody, Ocular melanoma-associated antigen antibody, OMA81H antibody, PTLGP40 antibody, Tetraspanin 30 antibody, Tetraspanin-30 antibody, Tspan 30 antibody, Tspan-30 antibody, TSPAN30 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CD63 recombinant protein (Position: E97-M238). Human CD63 shares 74% and 73% amino acid (aa) sequence identity with mouse and rat CD63, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.