HP-1α (clone 5E3), anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP63830
Catalog Number: AC-AP73355
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Other Names:
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Antigen Type: Recombinant Protein
Antigen Type: CBX5
Gene ID: 23468
Primary Accession: P45973
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Other Names:
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Antigen Type: Recombinant Protein
Antigen Type: CBX5
Gene ID: 23468
Primary Accession: P45973
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