CD68/CD68 (kpi) polyclonal (Center), anti-human
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In stock
SKU
AC-AP17393C
Catalog Number: AC-AP17393C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36354
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36354
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
Other Names:
Macrosialin, Gp110, CD68, CD68
Target/Specificity:
This CD68/CD68 (kpi) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-237 amino acids from the Central region of human CD68/CD68 (kpi).
Antigen Region:
209-237
Antigen Type: Synthetic Peptide
Gene Name: CD68
Gene ID: 968
Primary Accession: P34810
NCBI Accession: NP_001035148.1;NP_001242.2
Other Accession: NP_001242.2;NP_001035148.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
Other Names:
Macrosialin, Gp110, CD68, CD68
Target/Specificity:
This CD68/CD68 (kpi) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-237 amino acids from the Central region of human CD68/CD68 (kpi).
Antigen Region:
209-237
Antigen Type: Synthetic Peptide
Gene Name: CD68
Gene ID: 968
Primary Accession: P34810
NCBI Accession: NP_001035148.1;NP_001242.2
Other Accession: NP_001242.2;NP_001035148.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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