CD68 monoclonal(Ascites), anti-human
€470.00
In stock
SKU
AC-AM1996a
Catalog Number: AC-AM1996a
Size: 100 µl
Isotype: mouse IgG1
Clone Name: 404CT9.2.5
Applications: WB
Datasheet
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Size: 100 µl
Isotype: mouse IgG1
Clone Name: 404CT9.2.5
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
Other Names:
Macrosialin, Gp110, CD68, CD68
Target/Specificity:
This CD68 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from human CD68.
Antigen Region:
133-160
Antigen Type: Synthetic Peptide
Gene Name: CD68
Gene ID: 968
Primary Accession: P34810
NCBI Accession: NP_001035148.1;NP_001242.2
Other Accession: NP_001242.2;NP_001035148.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
Other Names:
Macrosialin, Gp110, CD68, CD68
Target/Specificity:
This CD68 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from human CD68.
Antigen Region:
133-160
Antigen Type: Synthetic Peptide
Gene Name: CD68
Gene ID: 968
Primary Accession: P34810
NCBI Accession: NP_001035148.1;NP_001242.2
Other Accession: NP_001242.2;NP_001035148.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
| Is Featured? | No |
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