CD68 Polyclonal Antibody

Background:
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Research Area: Cancer, Immunology

Synonyms:
CD 68, CD68, CD68 antigen, CD68 molecule, CD68, DKFZp686M18236, gp11, Gp110, LAMP4, Macrophage antigen CD68 (microsialin), MACROPHAGE ANTIGEN CD68, Macrosialin, SCARD1, Scavenger receptor class D member 1

Immunogen: Synthetic peptide of human CD68

Swissprot: P34810
Gene Accession: NP_001242

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-52998/sc-20060/sc-70761/sc-17832