CD7 (clone 124-1D1), anti-human

Source:
A BALB/c mouse was immunized with human leukocytes.
Fusion partner: NS-1.



Specifications:
124-1D1 recognizes 40 kDa CD7, a member of the immunoglobulin gene superfamily and expressed on the majority of immature and mature T-lymphocytes, and T-cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B-cells and on malignant B-cells. CD7 associates directly with phospoinositol and tyrosine phosphorylation. 124-1D1 was assigned at the IVth International Workshop.

Species reactivity:
Positive: human.

Applications:
Characterization of Leukemia and lymphoma.
Flow cytometry: +
Frozen sections: +
Immunofluorescence: +
Paraffin sections: ―

Positive control: Jurkat, HUT-78, Molt-4, CEM cells, or human PBL. Lymph node and tonsil.

References:
- Knapp W. et al. Leucocyte typing IV, p. 1076, Oxford University Press, Oxford (1989)