CD74 polyclonal, anti-human

Background:
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Synonyms: DHLAG, HLADG, II, Ia-GAMMA

Cellular Location: Cell membrane Endoplasmic reticulum membrane Endosome Golgi apparatus Lysosome Single-pass type II membrane protein trans-Golgi network

Immunogen:
Recombinant protein of human CD74

Gene Symbol: CD74

Gene ID: 972

Swiss prot: P04233

Calculated MW: 34kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.