CD79a polyclonal, anti-human
€428.00
In stock
SKU
BS90259
Catalog Number: BS90259
Size: 100 µl
Other Size: 50 µl
Isotype: rabbit IgG
Applications: WB, IF, IHC, FC
Questions? Contact us!
Size: 100 µl
Other Size: 50 µl
Isotype: rabbit IgG
Applications: WB, IF, IHC, FC
Questions? Contact us!
Background:
The mb-1 gene codes for a phosphoprotein, designated CD79a, that, together with the related CD79b protein, forms a dimer associated with membrane-bound immunoglobulin in B-cells. The CD79a/CD79b dimer is closely associated with the B-cell antigen receptor, in a similar manner to the association of CD3 with the T-cell receptor, and enables the cell to respond to the presence of antigens on its surface. The CD79a protein is present on the surface of B-cells throughout their life cycle, and is absent on all other healthy cells, making it a highly reliable marker for B-cells in immunohistochemistry. The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
Alternative Name:
CD79a, CD79A, IGA, MB1, B lymphocyte-specific MB1 protein, B-cell antigen receptor complex-associated protein alpha chain, CD 79a, CD79a, CD79a antigen (immunoglobulin-associated alpha), CD79A antigen, CD79a molecule, immunoglobulin-associated alpha, CD79A, Ig alpha, Ig-alpha, IGA, IgM-alpha, Immunoglobulin-associated alpha, Ly54, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein antibody
Application Dilution:
WB:1:500-1:1,000
IHC:1:50-1:200
IF:1:50-1:100
FC:1:50-1:100
Specificity: CD79a polyclonal antibody detects endogenous levels of CD79a protein.
Immunogen:
Recombinant protein within human CD79a aa 33-143.
MW: 38 kDa, predicted molecular weight 25 kDa.
Swiss-Prot: P11912 Human
Purification & Purity:
Protein A purified.
Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
For research use only, not for use in diagnostic procedure.
The mb-1 gene codes for a phosphoprotein, designated CD79a, that, together with the related CD79b protein, forms a dimer associated with membrane-bound immunoglobulin in B-cells. The CD79a/CD79b dimer is closely associated with the B-cell antigen receptor, in a similar manner to the association of CD3 with the T-cell receptor, and enables the cell to respond to the presence of antigens on its surface. The CD79a protein is present on the surface of B-cells throughout their life cycle, and is absent on all other healthy cells, making it a highly reliable marker for B-cells in immunohistochemistry. The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
Alternative Name:
CD79a, CD79A, IGA, MB1, B lymphocyte-specific MB1 protein, B-cell antigen receptor complex-associated protein alpha chain, CD 79a, CD79a, CD79a antigen (immunoglobulin-associated alpha), CD79A antigen, CD79a molecule, immunoglobulin-associated alpha, CD79A, Ig alpha, Ig-alpha, IGA, IgM-alpha, Immunoglobulin-associated alpha, Ly54, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein antibody
Application Dilution:
WB:1:500-1:1,000
IHC:1:50-1:200
IF:1:50-1:100
FC:1:50-1:100
Specificity: CD79a polyclonal antibody detects endogenous levels of CD79a protein.
Immunogen:
Recombinant protein within human CD79a aa 33-143.
MW: 38 kDa, predicted molecular weight 25 kDa.
Swiss-Prot: P11912 Human
Purification & Purity:
Protein A purified.
Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
For research use only, not for use in diagnostic procedure.
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