CD79a (T203) polyclonal, anti-human, mouse
€305.00
In stock
SKU
BS9006
Background:
CD79 (also designated Ig α/Ig β) is a heterodimer composed of α chains,designated CD79A or MB-1, and β chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immunoreceptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.
Alternative Name:
B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein, CD79a, IGA, MB1, CD79A
Application Dilution: IHC: 1:50~1:200
Specificity: CD79a (T203) polyclonal antibody detects endogenous levels of CD79a protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 171-220 of Human CD79a.
MW: ~33 kDa
Swis Prot.: P11912
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
CD79 (also designated Ig α/Ig β) is a heterodimer composed of α chains,designated CD79A or MB-1, and β chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immunoreceptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.
Alternative Name:
B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein, CD79a, IGA, MB1, CD79A
Application Dilution: IHC: 1:50~1:200
Specificity: CD79a (T203) polyclonal antibody detects endogenous levels of CD79a protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 171-220 of Human CD79a.
MW: ~33 kDa
Swis Prot.: P11912
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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