CD8.2 (clone F4) FITC, anti-mouse
€224.00
In stock
SKU
ARP-06-1022-4
Catalog Number: 06-1022-4
Size: 50 µg
Isotype: Mouse IgM
Size: 50 µg
Isotype: Mouse IgM
Background:
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
Decription:
Mouse monoclonal Antibody to Mouse CD 8.2, FITC conjugate
Synonyms: CD8.2
Clone: F4
Isotype: Mouse IgM
Immunogen: Purified CD8+ Mouse LN cells
Reactivity: mouse
Specificity: Mouse CD 8.2, Lyt-2.2 allele
Form: Affinity Purified, in PBS containing 0.5% BSA and 0.1% Sodium Azide
Applications: Staining, sorting, panning, immunoprecipitation, and antibody mediated cytotoxicity
Working Dilution: For flow cytometry, dilute 1:1 and add 2.5-5 ul per 106 cells
Storage: 2-8C for immediate use; or at -20C (aliquot) Avoid freeze-thaw cycles
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
Decription:
Mouse monoclonal Antibody to Mouse CD 8.2, FITC conjugate
Synonyms: CD8.2
Clone: F4
Isotype: Mouse IgM
Immunogen: Purified CD8+ Mouse LN cells
Reactivity: mouse
Specificity: Mouse CD 8.2, Lyt-2.2 allele
Form: Affinity Purified, in PBS containing 0.5% BSA and 0.1% Sodium Azide
Applications: Staining, sorting, panning, immunoprecipitation, and antibody mediated cytotoxicity
Working Dilution: For flow cytometry, dilute 1:1 and add 2.5-5 ul per 106 cells
Storage: 2-8C for immediate use; or at -20C (aliquot) Avoid freeze-thaw cycles
| Is Featured? | No |
|---|
Write Your Own Review