CD8 (clone C12) biotin, anti-human

Background:
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

Decription:
Mouse monoclonal Antibody to Human CD8, Biotin conjugate

Synonyms: CD8A, CD8

Clone: C12

Isotype: Mouse IgG2

Immunogen: Purified Human CD8+ peripheral blood T cells

Reactivity: human

Specificity: Human CD8

Form: Affinity Purified, in PBS containing 0.5% BSA and 0.1% Sodium Azide

Applications: Staining antibody, weakly cytotoxic.

Working Dilution: For staining, use 10µl/106 cells

Storage: 2-8C for immediate use; or at -20C (aliquot) Avoid freeze-thaw cycles