CD8 (clone RAVB3), anti-human

Background:
CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.

Synonyms: MAL, p32, Leu2, CD8A

Cellular Location: Membrane Secreted

Immunogen:
Purified recombinant fragment of human CD8 expressed in E. Coli.

Gene Symbol: CD8

Gene ID: 925

Swiss prot: P01732

Recommended dilution:
FCM 1:200-400

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.