CD80 rabbit polyclonal, anti-human, mouse, rat

Backgroud: The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011],function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.,tissue specificity:Expressed on activated B-cells, macrophages and dendritic cells.,

Synonyms: T-lymphocyte activation antigen CD80 (Activation B7-1 antigen, BB1, CTLA-4 counter-receptor B7.1, B7, CD antigen CD80)

Gene Name: CD80 CD28LG CD28LG1 LAB7

Gene ID: 941

SwissProt ID: P33681

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.