CD82 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
CD82(Cluster of Differentiation 82), also named KAI1, is a human protein encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma(ESCC). And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1.

Description:
Rabbit IgG polyclonal antibody for CD82 antigen (CD82) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
4F9 antibody, Antigen detected by monoclonal and antibody IA4 antibody, C33 antibody, C33 antigen antibody, CD 82 antibody, CD82 antibody, Cd82 antibody, CD82 antigen antibody, CD82 molecule antibody, CD82_HUMAN antibody, GR 15 antibody, GR15 antibody, IA 4 antibody, IA4 antibody, Inducible membrane protein antibody, Inducible membrane protein R2 antibody, KAI 1 antibody, KAI1 antibody, Kangai 1(suppression of tumorigenicity 6, prostate; CD82 antigen(R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4) antibody, Kangai 1 antibody, Kangai1 antibody, Metastasis suppressor Kangai 1 antibody, Metastasis suppressor Kangai-1 antibody, Metastasis suppressor Kangai1 antibody, R2 antibody, R2 leukocyte antigen antibody, SAR 2 antibody, SAR2 antibody, ST 6 antibody, ST6 antibody, Suppression of tumorigenicity 6 antibody, Suppression of tumorigenicity 6 prostate antibody, Suppressor of tumorigenicity 6 antibody, Suppressor of tumorigenicity 6 protein antibody, Tetraspanin 27 antibody, Tetraspanin-27 antibody, Tetraspanin27 antibody, Tspan 27 antibody, Tspan-27 antibody, Tspan27 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human CD82(253-267aa CRHVHSEDYSKVPKY), different from the related mouse and rat sequences by two amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of human CD82(253-267aa CRHVHSEDYSKVPKY), different from the related mouse and rat sequences by two amino acids.

Form: Liquid; Each vial contains 50% glycerol, 0.9mg NaCl, 0.2mg Na2HPO4.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Storage: At -20˚C for one year, at 4˚C for one month. Avoid repeated freezing and thawing.