CD82 Polyclonal Antibody

Background:
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research Area: Immunology,Epigenetics and Nuclear Signaling,Cancer

Synonyms:
CD82, 4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27

Immunogen: A synthetic peptide of human CD82 (NP_002222.1).

Swissprot: P27701
Gene ID: 3732

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.