CD86 antibody (clone 3D7), anti-human
€435.00
In stock
SKU
AC-AT1449a
Catalog Number: AC-AT1449a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: IP
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: IP
Request Information AC-AT1449a">Request Information
Background:
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.
Other Names:
T-lymphocyte activation antigen CD86, Activation B7-2 antigen, B70, BU63, CTLA-4 counter-receptor B72, FUN-1, CD86, CD86, CD28LG2
Antigen Type:
Recombinant Protein
Gene Name: CD86
Gene ID: 942
NCBI Accession: NP_001193853.1;NP_001193854.1;NP_008820.3;NP_787058.4;NP_795711.1
Primary Accession: P42081
Other Accession: BC040261
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.
Other Names:
T-lymphocyte activation antigen CD86, Activation B7-2 antigen, B70, BU63, CTLA-4 counter-receptor B72, FUN-1, CD86, CD86, CD28LG2
Antigen Type:
Recombinant Protein
Gene Name: CD86
Gene ID: 942
NCBI Accession: NP_001193853.1;NP_001193854.1;NP_008820.3;NP_787058.4;NP_795711.1
Primary Accession: P42081
Other Accession: BC040261
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
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