CD89 Polyclonal Antibody

Background:
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Research Area: Cancer, Immunology

Synonyms:
CD89, Fc alpha receptor, Fc fragment of IgA, receptor for, FCAR, FCAR, IgA Fc receptor, Immunoglobulin alpha Fc receptor

Immunogen: Recombinant protein of human FCAR

Swissprot: P24071
Gene Accession: BC027953

Calculated MW: 32 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-17084/sc-17086/sc-17083/sc-17082/sc-20927